Osteoarthritis (OA) is a chronic disease that usually affects the hands, knees and hips.1,2 The main symptoms are joint pain and stiffness that usually develop slowly over time.3 It can get to a point where everyday tasks can become difficult.3
There is a rapid increase in OA prevalence after the age of 45 years,1 with the latest snapshot stating 1 in 5 Australians over 45 years old suffer from OA.1 Given the ageing population, the number of Australians with OA is expected to increase.1
Traditionally OA was thought to be a non-inflammatory disease resulting from “wear and tear” that leads to loss of cartilage.2,4 However, research into the condition has revealed that inflammation plays a role in OA pain.4,5 In a holistic management approach for OA sufferers, pain management is an important aspect.1
Guidelines for the pharmacological management of OA pain have changed1
To reflect changing evidence in the field of osteoarthritis, the Royal Australian College of General Practitioners (RACGP) updated its guideline for the management of knee/hip OA in 2018.1
|Recommendation for1||No recommendation for or against1|
Paracetamol has long been considered first-line therapy for OA, however there is no longer a recommendation for or against the use of paracetamol as current evidence suggests the reduction in OA pain is too small to be of clinical relevance.1NSAIDs taken orally have been demonstrated to reduce pain and increase function in patients with knee/hip OA and are possibly more effective than paracetamol for most people.1 It may be reasonable to trial them at the lowest effective dose and discontinue use if not effective.1Alongside pharmacological options, supporting education about the condition and the importance of weight loss and movement is crucial for OA management.1As part of an integrated care approach, Nurofen tablets help to relieve the pain of osteoarthritis for up to 8 hours6-8†
On flare-up days, choose Nurofen for long-lasting relief.6-8 Plus, consistent, high-level evidence shows that Nurofen is as well tolerated as paracetamol and agreeable to most people.9,10**
†Two tablets of Nurofen 200mg provides up to 8 hours of relief.6-8 **When taken as directed in an over-the-counter setting in people without contraindications/precautions.9,10
- The Royal Australian College of General Practitioners. Guideline for the management of knee and hip osteoarthritis. 2nd East Melbourne, Vic: RACGP, 2018.
- Kielly J et al. CPJ/RPC 2017;150(3):156–
- Arthritis & Osteoporosis New South Wales. Osteoarthritis. Available at: https://www.arthritisnsw.org.au/about-arthritis/types-of-arthritis/osteoarthritis/ (accessed 2 July 2019).
- Berenbaum F. Osteoarthritis Cartilage 2013;21(1):16–21.
- Chen D et al. Bone Res 2017;5:16044.
- Mehlisch DR et al. Clin Ther 2010;32(6):1033–1049.
- Malmstrom K et al. Clin Ther 1999;21(10):1653–1663.
- Malmstrom K et al. Clin Ther 2004;26(5):667–679.
- Moore N et al. Clin Drug Invest 1999;18:89–98.
- Rampal P et al. J Int Med Res 2002;30:301–308.
Nurofen contains 200mg ibuprofen. For the temporary relief of pain and/or inflammation. This medicine may not be right for you. Read the label before purchase. Follow the directions of use. Incorrect use could be harmful. If symptoms persist, talk to your health professional.
Nurofen Double Strength contains 400mg ibuprofen. For the temporary relief of pain and/or inflammation. Ask your pharmacist – they must decide if this product is right for you. This medicine may not be right for you. Read the label before purchase. Follow the directions of use. Incorrect use could be harmful. If symptoms persist, talk to your health professional.
®NUROFEN is a registered trademark of the Reckitt Benckiser Group of Companies. Level 47, 680 George St, Sydney 2000, NSW Australia. NUR0686 July 2019.